Susana Moreira (EDT), Miguel Gama (EDT) Carbohydrate Binding Modules

Annotation

Carbohydrates play an important role in many biological and biochemical processes, including the fertilization, cell differentiation and maturation,protein folding and degradation[6]. Carbohydrates are also involved in a variety of recognition events, such as cell-cell and cell-matrix interactions. Many of these are immunologically relevant processes, namely inflammation host-pathogen interactions, immune response and health disorders, such as arthritis, Alzheimer's disease, among others. Carbohydrate-active enzymes(CAZymes) play key roles in glycobiology. They are involved in the synthesis and degradation of complex carbohydrates and glyco-conjugates.