Horst Bluethmann (EDT), Pamela Ohashi (EDT) Transgenesis and Targeted Mutagenesis in Immunology

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Investigations into the field of immunology are rapidly expanding with the use of genetically altered mice at the embryonic stage. This breakthrough laboratory guide provides a complete study of transgenesis and targeted mutagenesis in laboratory mice that will be valued by researchers looking for fresh observations and interpretations when designing future experiments.Special Features Include:Contributions of two Nobel Prize winnersAddresses the use of mouse models in studying the immune systemTargets gene distribution in embryonic stem cells and their introduction into blastocyte mice modelsAnalyzes the in vivo functional loss of embryonic cellsA practical, useful guidebook for individual researchers, laboratories, and libraries