Joseph S. Bertino, Angela Kashuba, Joseph D. Ma, Uwe Fuhr, C. Lindsay DeVane Pharmacogenomics An Introduction and Clinical Perspective

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A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICSThe only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus an examination of the latest technologies that are constantly reshaping the field. Pharmacogenomics is cohesively organized into two sections, the first of which reviews basic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a "mini" course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties.FEATURES Important overview of general pharmacogenomics and pharmacogenetics concepts, including genetic variation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomicsDiscussion of regulatory considerations in pharmacogenomicsFocus on the role of health care professionals along with a review of related privacy issues, as well as broader ethical, legal, and social considerationsIn-depth chapters on drug metabolism and transportersPractical, step-by-step guidance on public access to pharmacogenomic testing and patient counselingUp-to-date coverage of non-genetic influences on pharmacogenomicsEmphasis on gene-drug interactionsNumerous tables and figuresChapter-ending referencesConcise learning objectives at the beginning of each chapterCase studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty